Cover image about Alzheimer's disease

Treatment and prevention of neurodegenerative Alzheimer's disease in Turkey

Curative treatment of Alzheimer's disease (dementia) is not possible at the present time, only treatment is available for the symptoms of the disease and modern methods are used to treat Alzheimer's disease in Turkey that have proven effective. Follow us to learn about them.

Alzheimer's disease treatment

Alzheimer's disease is a progressive chronic neurodegenerative disease, meaning that it continues throughout the life of the patient and gets worse over time. mostly the elderly.

In this disease, mutant proteins (amyloid protein and tau protein) are formed that surround or are inside neurons. This leads to disruption of brain functions due to severing the connections of these cells with each other and depriving them of carrying out the basic operations necessary for their survival.

This results in the death of these neurons and the loss of the neurotransmitters that they produce. A shortage of neurotransmitters occurs in the brain as a result, which leads to neuronal Alzheimer’s disease, so the treatment of Alzheimer’s disease depends on relieving Alzheimer’s symptoms.

Image showing the mechanism of Alzheimer's disease and the accumulation of amyloid proteins around nerve cells
The mechanism of Alzheimer's disease and the accumulation of amyloid proteins around neurons

Alzheimer's disease is treated with drugs that inhibit cholinesterase or other drugs that antagonize the effect of NMDA, and these are the two drug groups used that we will discuss in detail.

One of the newer ways to treat Alzheimer's disease is TPS transcranial pulse stimulation In which ultrasound waves (advanced echo) are applied to the head over several sessions. This method showed a remarkable improvement in many patients. This method is applied in Bimaristan Medical Center in Turkey.

Treating symptoms secondary to Alzheimer's disease

Alzheimer's disease has many symptoms besides memory loss. Click here to learn about the symptoms and causes of Alzheimer's diseaseSome of these symptoms include:

  • Depression
  • Anxiety and mental disorders
  • Anger and ease of irritation
  • hallucinations
  • sleep disturbance

These symptoms are treated with some symptomatic medications, including:

  • Antidepressants
  • Anti-parkinsonism
  • antiepileptics
  • Anxiety situations
  • antipsychotics
  • beta blockers
  • Antibodies directed at amyloid

Treatment of early stage Alzheimer's disease

The patient initially suffers from weakness in memory and thinking ability. Treatment at this stage can stop or delay the progression of the disease and is therefore very necessary.

Treatment of Alzheimer's disease in the early stage relies on mental exercises with the prescription of anticholinesterases. This enzyme breaks down acetylcholine in synapses after it has done its job (a natural process).

Treatment of early Alzheimer's disease with cholinesterase inhibitors

Acetylcholine is one of the neurotransmitters present in the brain and is responsible for attention and memory. When nerve cells die in the brain due to being surrounded by mutant proteins, this neurotransmitter decreases.

Cholinesterase inhibitors increase the concentrations of acetylcholine in the brain by stopping its breakdown. We note the high effectiveness of these drugs in treating early Alzheimer's disease and relieving its primary and secondary symptoms (such as depression and irritability).

Cholinesterase inhibitors that are effective in treating Alzheimer's disease (dementia):

  • Rivastigmine
  • Donepezil
  • Galantamine

Despite the great benefit of treating Alzheimer's disease using cholinesterase inhibitors (drug treatments), a study revealed some side effects that people (Alzheimer's patients) may feel when using a drug, including:

  • nausea
  • vomiting
  • diarrhea
  • Dizziness and lightheadedness
  • slowness of movement
  • Fainting
  • Injuries and bruises due to fainting and falling to the ground (such as fractures).

Treatment of early Alzheimer's disease using mindfulness exercises

Continuous mental activity shows promising results in the treatment of Alzheimer's patients in terms of slowing the progression of the disease, as many doctors advise patients at risk of developing the disease to keep their brains active.

This is done through mental puzzles and thinking games such as crosswords and others. The aim of this mental activity is to stimulate the patient's brain and make him try to think and remember things.

This activity must be enthusiastic for the patient, harmonize with the atmosphere, and be competitive in it, but it is strictly required to preserve the patient's dignity and take into account his mental capacity, which is declining due to illness, and not to provoke or anger him because of these games.

Treatment of Alzheimer's disease in its advanced stages

When Alzheimer's disease progresses and the most severe symptoms of its path occur, new treatment options for Alzheimer's (dementia) are more effective.

For the treatment of the late stages of Alzheimer's, there is a new drug group called NMDA receptor blockers, or it is possible to rely on the aforementioned drug, but with higher doses and different methods of administration.

Treatment of Alzheimer's disease with an NMDA receptor-blocking drug

These drugs are based on improving the transmission of neurotransmitters in the central nervous system and stopping damage to the brain (destruction of brain cells) and thus treatment by improving Alzheimer's symptoms.

Memantine is used to treat Alzheimer’s patients in the late stage, which is a drug that is bound to the aforementioned receptors and can be combined with cholinesterase inhibitors to improve the efficiency of treatments (according to the Food and Drug Administration in the United States of America).

Image showing a box of memantine, a drug used to treat Alzheimer's disease
Memantine, a drug used to treat Alzheimer's disease

One of the most famous of these drug combinations is the use of memantine with donepezil, as a study revealed the effectiveness of this combination in stabilizing and treating advanced Alzheimer's disease.

Among the side effects of memantine, we mention:

  • Dizziness and lightheadedness
  • headache
  • drowsiness
  • constipation
  • Confusion

Treatment of advanced Alzheimer's disease with rivastigmine

It is one of the aforementioned cholinesterase inhibitors, but in the advanced case of Alzheimer's disease, treatment is done with Rivastigmine skin patches (drugs used when the patient's condition deteriorates with Alzheimer's disease).

These patches release the drug, which is continuously absorbed by the skin throughout the period of placing the patch. The dose of rivastigmine in treatment here ranges between 13.3-4.6 mg per day (the daily dose).

The latest technology in Alzheimer's disease treatment in Turkey

Alzheimer's disease is treated in Turkey using TPS transcranial pulse stimulationThis method depends on stimulating the nerve cells in the brain and activating the deep areas of the brain. This method has shown great success in treating and improving the symptoms of Alzheimer’s patients.

Alzheimer's disease diagnosis

People with Alzheimer's disease are predicted through some examinations during a doctor's interview, as the disease is revealed when the patient is asked about where he is and what time is now.

He also tests his memory of recently learned things (short-term memory), and important things that happened during his life (long-term memory), then he may check his general health such as temperature and blood pressure along with the functions of all other devices.

This remains all just a prediction, as despite this, Alzheimer's disease can only be diagnosed now after the death of the patient and his brain is examined anatomically and under a microscope.

Sometimes we can rely on CT or MRI scans that help us get closer to a better diagnosis during the patient's life through the shape of the brain in the images.

Changes that indicate excessive damage to the brain and lack of cerebral matter appear in the advanced stages of dementia and Alzheimer’s. Here, the treatment of the disease is no longer effective, and it must be treated with the most effective modern methods.

Image illustrating cerebral atrophy due to Alzheimer's disease
Cerebral atrophy due to Alzheimer's disease, and we see similar images on magnetic resonance imaging

At this stage Contact us To provide you with the support you need to treat your condition (for Alzheimer's disease), we will provide you with the best treatment in Turkey's hospitals.

Alzheimer's prevention

There is no proven evidence of effective prevention against Alzheimer's disease, but the opposite of risk factors (leading to the death of brain cells in Alzheimer's disease) remain the most important ways to prevent Alzheimer's disease or delay its development.

Despite this, there are methods to prevent Alzheimer's disease (aging), according to the results of a promising study, including the following:

  • Keeping the brain active: We must not leave our brains idle. Continuous reading and continuous education are the basis of a healthy life. The mind must also be filled with some riddles and puzzles.
  • Avoid smoking: Smoking is a risk factor for Alzheimer's disease.
  • Live a healthy life: And by eating healthy food, especially that contains olive oil and fish, it is also preferable to be exposed to beneficial sunlight to obtain vitamin D.
  • Maintaining a healthy social life: This is done by meeting with friends and donating in charitable projects so that the person feels satisfied with himself and his achievement by being an active member of society.
  • Playing sports: Sport is useful in many diseases, so keeping the body healthy is important to prevent disease.
  • Sleeping well: Staying up late and lack of sleep are among the causes of Alzheimer's disease, according to a study on brain cells of Alzheimer's patients.

He will secure Bimaristan Medical Center correct medical advice for you in the treatment of disease, Contact us In order to guide you to the most skilled doctors and the best hospital in Turkey to treat your health condition.


Sources:

  1. MedScape
  2. healthline
  3. NHS

Common Questions

Alzheimer's disease is considered a fatal disease in its last stages, and the most fatal thing for people with it is their inability to swallow properly, which leads to suffocation and death.

Treatment in dementia consists of two parts. The first is pharmacological. For the treatment of Alzheimer’s disease, there are cholinesterase inhibitors such as rivastigmine, and drugs used in the treatment of advanced Alzheimer’s disease, including memantine.

The second part of Alzheimer's treatment consists of mental exercises, puzzles and riddles that are entertaining to the patient and may be effective in treating and delaying the progression of dementia (which is already present in a person with dementia).

Alzheimer's disease is treated in Turkey by TPS . Transcranial Impulse Stimulation.

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