}7 April, 2022
jDr.. Muhannad Al-Khatib

All you need to know about chemoembolization

}7 April, 2022
jDr.. Muhannad Al-Khatib

All you need to know about chemoembolization

Table of Contents

     

    Chemoembolization is one of the latest treatment methods with minor side effects, and this method has seen qualitative leaps in Turkey for the efficiency of doctors and devices.

    What is chemoembolization?

    Chemoembolization (a method used in chemotherapy) or what is called transarterial chemoembolization (TACE) is a type of chemotherapy and modern therapeutic (or palliative) methods include both chemotherapy and coagulation to relieve the symptoms of the tumor and reduce it by killing Tumor cells, similar to radioembolization (interventional treatment), but the difference here is that we inject chemicals that kill cancer cells instead of small particles loaded with radioactive isotopes, and this chemotherapy method is often used in Liver cancer treatment Hepatocellular cancer (HCC), whether it is primary (that is, it originated in the liver) or has spread to it from other organs.

    Chemoembolization in Turkey.

    Chemoembolization in Turkey.

    Chemoembolization is a minimally invasive procedure that is performed by a radiologist and is almost similar to angiography in terms of mechanism.

    Embolization is done by injecting embolizing materials that block the blood vessels feeding the tumor, and prevent the spread of the chemotherapy effect to other areas.
    We can use chemoembolization alone, or we can combine it with other treatments such as radiotherapy, as it has been proven Studies Survival improvement in patients with hepatocellular carcinoma when combined radiotherapy with chemoembolization, chemotherapy or radiofrequency ablation…

    What are the features of chemoembolization therapy?

    Chemoembolization has several advantages that distinguish it from other conventional treatment methods of treatment, including:

    • Prevents the delivery of oxygen carried in the blood to the tumor, which contributes to shrinking the size of the tumor and killing cancer cells.
    • Because the chemical dose will be injected directly into the tumor, a larger dose of chemotherapy can be given in chemoembolization than the dose used in standard chemotherapy.
    • Arterial blood clots and the perfusion of cancer in this procedure prevents the chemotherapy from spreading to nearby areas.
    • Symptoms in this chemotherapy are significantly less and lighter because of what we mentioned earlier.

    When do we use TACE chemoembolization?

    Doctors often resort to this method when other methods have failed or patients are too ill to undergo more aggressive treatments (such as surgery).
    Chemoembolization is most useful for patients whose disease is mostly confined to the liver, whether the tumor begins in the liver or has spread (metastatic cancer) from another organ.

    Cancers that can be treated with chemoembolization include:

    • Hepatocellular carcinoma
    • bile duct cancer
    • Some of the cancers that give hepatic metastases:
      • Colon Cancer
      • breast cancer
      • Carcinoid tumors and other neuroendocrine tumors
      • pancreatic islet tumors
      • Melanoma of the eyeball

    How do patients prepare for chemoembolization in Turkey?

    Your doctor will recommend several tests, including blood tests and liver function tests. A CT scan or MRI of your liver may also be done before chemoembolization.

    The doctor prescribes some sedative medications and stops any medication the patient is taking that may interfere with the process (including aspirin).

    After the results of the tests appear, the doctor must make sure that there is no blockage in the hepatic blood flow (portal vein obstruction), cirrhosis of the liver, or any blockage in the bile ducts.

    The patient will be asked to stop eating or drinking after midnight the night before the chemoembolization treatment. Patients usually stay in the hospital anywhere from 1-4 nights after the procedure. The procedure is performed by an interventional radiologist in the Department of Interventional Radiology. The patient has an intravenous line, through which intravenous fluids, antibiotics and sedatives are given.

    How is Chemoembolization (TACE) performed in Turkey?

    In chemoembolization therapy in Turkey, the efforts of the best doctors, elite nurses and the best modern medical devices will combine to facilitate the process of chemotherapy coupled with chemoembolization in the best way and achieve the best results at the lowest possible cost. 

    X-rays will be taken to map the pathway of the blood vessels feeding the tumor. The patient may be given a drug called allopurinol, which helps protect the kidneys from chemotherapy and byproducts produced by dying tumor cells.

    The interventional radiologist will place a small catheter (a transcatheter tube) in an artery in the groin and perform an arterial Gram arteriogram that specifically examines the arteries in the liver.
    In the process of chemical chemoembolization, the doctor may use local anesthesia, and the process of chemical chemoembolization does not require intubation of the patient, however, some patients may need general anesthesia and local anesthesia is not sufficient.

    The doctor will make a very small skin incision at the site.
    Using X-ray guidance, a doctor inserts a thin catheter through the skin into the arterial pathway, either in the groin or in the wrist, and then pushes it into the liver. Injecting contrast material is injected through the catheter and another series of X-ray images are taken.
    Once the catheters are placed in the arterial branches that feed the tumor, anticancer drugs and embolizing agents are mixed together and injected.

    Contrast imaging with injection and note in B tumor perfusion after chemoembolization.

    Contrast imaging with injection and note in B tumor perfusion after chemoembolization.

    Additional x-rays will be taken to make sure that the chemotherapy treatment has reached the cancer and the arterial thrombosis of the cancer is complete.
    When the procedure is complete, the doctor removes the catheter and applies pressure to stop any bleeding. Sometimes, the doctor may use a closure device to block the small opening where the catheter was inserted. This will allow you to heal more quickly. There are no visible stitches on the skin.

    Your doctor may provide you with medications to help prevent nausea and pain and antibiotics to help prevent infection and sepsis after the procedure. The patient is expected to be discharged from the operating room after treatment with a blood clotting agent after 6 hours depending on which artery was used.

    Complications and Side Effects of Chemoembolization (TACE .)

    After the procedure, patients may have varying degrees of pain, fever and nausea, these symptoms may last from a few hours to a few days, and can be treated easily as the operation doctor prescribes medications that help get rid of these symptoms, the patient may also notice slight hair loss, rarely What anyone else notices.

    Serious complications of chemoembolization are rare.
    In less than 3% of procedures, a cancer treated with chemoembolization as a result of the procedure may become infected and an abscess may form.

    One case of hepatic failure due to arterial chemoembolization (TACE) was reported among 100 surgeries.

    Care after Chemoembolization in Turkey

    Care after chemoembolization in Turkey.

    Care after chemoembolization in Turkey.

    The patient should be able to resume his normal daily activities within a week of chemoembolization treatment in Turkey.

    During the first month following chemotherapy combined with arterial chemoembolization, the patient should routinely see the doctor, inform him of any problems and monitor the progress of his recovery.
    He or she may need a CT or MRI scan and blood tests to determine the size and condition of the cancer being treated.

    The liver is divided into two parts: the right hepatic lobe and the left hepatic lobe. If there is a tumor that includes both lobes, this is usually treated in a phased manner. During the first preparation, one of the lobes is treated, the second lobe is usually treated after about a month.
    A CT or MRI scan is recommended every three months thereafter to determine how much the cancer has shrunk, and to see if new tumors appear in the liver.
    The median time before the second round of chemoembolization TACE (due to a new tumor) is between 10 and 14 months.

    TACE Chemoembolization can be repeated several times over many years, as long as it is still technically feasible for the patient to be healthy enough to tolerate the repeated procedures.

    Why should I choose treatment in Turkey?

    Recently, Turkey has become one of the leading countries in the field of medical tourism in the world.
    The reason for this is due to the presence of advanced medical centers that provide appropriate treatment by the most skilled doctors and the latest medical devices at a low cost.
    and stay Bimaristan Medical Center It is your first choice For treatment in Turkey.
    We guide you to the best expert specialists in all departments.
    We facilitate the language of communication between you and everyone through specialized Arab doctors who will help you communicate with your doctor.
    We help you secure the right treatment and high-end service in the most modern hospitals and medical centers in Turkey.
    We provide our services extensively and precisely.
    We accompany you step by step towards recovery.
    Free consultations around the clock.
    don't hesitate toContact usBimaristan, your family center in Turkey.

     


    Sources

    1. RadiologyInfo
    2. OncoLink
    3. JohnHopkinsMedicine
    4. UCLAHealth

    Frequently Asked Questions About Chemoembolization In Turkey

    What is TACE?

    It is a minimally invasive procedure that combines chemotherapy and vascular embolization via the arterial route to achieve the best possible results.

    What is the difference between chemoembolization and regular chemotherapy?

    Chemoembolization is used in the event that other treatments fail or the patient is unable to undergo prolonged courses of chemotherapy, and it is better in terms of reducing side effects, increasing the dose of the drug and cutting the perfusion of the tumor.

    Is chemoembolization dangerous?

    Chemoembolization is a minimally invasive procedure that does not carry serious complications and does not have many side effects, and due to the advancement of post-operative care methods significantly in Turkey, the complications have decreased dramatically.

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