}May 20, 2022
jDr.. Muhannad Al-Khatib

Newer Alzheimer's Treatment/Transcranial Pulsed Stimulation

}May 20, 2022
jDr.. Muhannad Al-Khatib

Newer Alzheimer's Treatment/Transcranial Pulsed Stimulation

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    Transcranial Pulsed Stimulation (TPS) is one of the newer ways in Turkey to treat Alzheimer's disease by applying ultrasound waves to areas of the cerebral cortex in order to stimulate the brain.

    Alzheimer's disease

    Alzheimer's Disease (AL) is one of the most common types of dementia in the elderly, with an incidence exceeding 8% after the age of 65 years and reaching 50% after the age of 85 years. The number of people with Alzheimer's disease in Turkey is estimated at 600,000.

    Alzheimer's disease is caused by the gradual degeneration of nerve cells and nerves with age, and Alzheimer's patients suffer from symptoms of memory loss and many problems in thinking, language and orientation, and thus the inability to live their lives without assistance.

    Alzheimer's disease or dementia in general is a polymorphic disease that results from various causes such as deposition of special proteins (tau, beta-amyloid), inflammation, lack of blood supply, and others.

    A diagnosis of Alzheimer's disease carries many psychological effects and changes the lives of both patients and their families as an incurable disease.

    Alzheimer's disease treatment in Turkey

    Despite the efforts made in the medical field to treat Alzheimer's, it is still incurable.
    Nevertheless, there has been remarkable progress in addressing this situation. Medications such as acetylcholinesterase inhibitors can slow the progression of symptoms and maintain stable mental functioning.

    In addition, many accompanying therapies are currently being used with the aim of developing the mental abilities of Alzheimer's patients and maintaining these abilities for as long as possible, thus improving the quality of life for these patients and reducing the burden on their relatives.

    It has evolved Treatment in Turkey Recently, its hospitals have been equipped with the latest technologies and advanced devices, in addition to specialized doctors who are able to take advantage of this rapid development in the medical field.

    Among this development, scientists have come up with a new tool that is considered a precedent in the field of Alzheimer's treatment andParkinson's disease It is “Transcranial Pulsed Stimulation (TPS) using the NEUROLITH device” which is only available in Turkey and some other countries and not others.

    NEUROLITH Deep Brain Stimulation Device for Alzheimer's Disease

    NEUROLITH Deep Brain Stimulation Device for Alzheimer's Disease

    According tostudy New published in the journal ADVANCED SCIENCE, the results of research on the TPS technology are encouraging for the application of deep brain stimulation in clinical treatment.

    will Bimaristan Medical Center In Turkey, it takes care of all the services the patient needs in order to receive the optimal treatment for Alzheimer’s disease using the latest medical technologies and the best specialized doctors.

    Treatment of Alzheimer's with TPS in Turkey

    Treatment of Alzheimer's disease with transcranial pulse stimulation

    Treatment of Alzheimer's disease with transcranial pulse stimulation

    Transcranial Pulse Stimulation (TPS) using ultrasound is a treatment option approved since 2018 for the treatment of mild to moderate Alzheimer's disease.

    This technology aims to enhance the cognitive abilities of people suffering from Alzheimer's dementia and preserve these abilities for as long as possible by stimulating different areas of the brain.

    According tostudy Published by the medical journal PubMed, this tool has helped significantly reduce cortical atrophy in the brain in Alzheimer's patients, and thus improve the nervous function of these patients.

    TPS is a safe tool that is free from any future complications, painless, very well tolerated and performed on an outpatient basis without the need for a hospital stay.

    Transcranial pulse stimulation has been used for medical purposes successfully since the 1990s under the term “extracorporeal shock wave therapy” to treat a variety of conditions such as nonunion, tendon and muscle pain, heart failure and erectile dysfunction.

    It should be noted that many neurological patients like patients Parkinson's Multiple sclerosis, stroke and neuropathic pain - whose brain function can still be restored by activating functional neurons - can be treated with TPS technology as the only technology that can activate deep areas of the brain in a targeted, non-invasive way.

    How does TPS work?

    Working Principle of Transcranial Pulsed Stimulation for Alzheimer's Treatment

    Working Principle of Transcranial Pulsed Stimulation for Alzheimer's Treatment

    Transcranial Pulsed Stimulation is performed in Turkey by a special device called NEUROLITH that generates ultrasound waves that are sent to the damaged areas of the brain through the skull. These waves can reach a depth of 8 centimeters of the brain and precisely stimulate the damaged areas in the Alzheimer’s patient’s brain in order to treat them.

    The principle of action is the mechanical stimulation of the biological processes called “mechanical transduction” (the transduction is the transmission of the signal), which leads to an increase in the permeability of the nerve cell membranes and the stimulation of ion channels and the release of nitrite oxide NO, which causes vasodilatation and an increase in metabolic activity and has an anti-inflammatory effect and ultimately leads to Release of angiogenic growth factors and stem cell migration and differentiation.

    According tostudy New, DBS had a significant role in improving the CERAD score for cognitive function assessment in Alzheimer's patients by 12.8% during the first three months after treatment.

    The average duration of TCS treatment in Turkey is about 30 minutes per session, the full treatment usually requires 6 sessions spread over two weeks, and it is a non-invasive device that does not require surgical incisions so that the pulses penetrate the skin and skull without causing damage to them.

    What happens during a brain stimulation session?

    The Pulse Brain Stimulation session in Turkey is performed safely by doctors trained in the use of the NEUROLITH device. During the session, the patient sits in a comfortable chair so that he can move freely throughout the treatment period.

    He enters the patient's information into the device and then the gel is applied to the patient's head or hair (it is not necessary to shave the patient's head before the session) to ensure optimal transmission of the pulses (the gel used here is the same as the one used in the normal echocardiography).

    After that, the patient wears special glasses to determine the location of the head on the device, and the doctor moves the handle of the device on certain places of the patient's head so that the doctor and patient can see the areas of the brain that the waves have reached on the screen, and this continues for 30 minutes.

    Watch for more details about Deep Brain Stimulation for Alzheimer's Disease the video.

    If one of your relatives suffers from Alzheimer's disease, hurry upContact us To know more details about the price of TPS Alzheimer's treatment in Turkey and book your place in Bimaristan Medical Center.


    2. NeuroUp Clinic

    Frequently asked questions about Alzheimer's treatment with TPS in Turkey

    What is the benefit of transcranial pulse stimulation in the treatment of Alzheimer's disease?

    Treatment of Alzheimer's with TPS has shown impressive results in improving speech abilities, memory, sense of direction, and significantly improving the CERAD score in Alzheimer's patients.

    What are the medical uses of transcranial pulse stimulation?

    TPS is used to treat a variety of neurological diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, neuralgia, bone dysplasia, muscle and tendon pain, erectile dysfunction, and wound healing. 

    How can Alzheimer's be treated using deep brain stimulation in Turkey?

    TPS works by generating ultrasound waves that mechanically stimulate a vital process called mechanical transduction that leads to increased cell metabolism and release of NO and many growth factors. There is also an anti-inflammatory effect as well as activation of stem cells and the congenital immune system.

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