Antenatal-non-surgical exam
}August 18, 2021
jDr.. Muhannad Al-Khatib

Non-Surgical Prenatal Test - All you need to know about Non-Surgical Prenatal Test

Non-invasive prenatal testing (NIPT) is a revolutionary advance in prenatal screening. The non-invasive prenatal test is a simple, high-resolution blood test.
}August 18, 2021
jDr.. Muhannad Al-Khatib

Non-Surgical Prenatal Test - All you need to know about Non-Surgical Prenatal Test

Non-invasive prenatal testing (NIPT) is a revolutionary advance in prenatal screening. The non-invasive prenatal test is a simple, high-resolution blood test.

Table of Contents

    Non-invasive prenatal testing (NIPT) is a revolutionary advance in prenatal screening. The non-invasive prenatal test is a simple, high-resolution blood test.

    NIPT Non-invasive Prenatal Test

    NIPT Non-invasive Prenatal Test

    Non-surgical prenatal testing helps diagnose common chromosomal abnormalities in the fetus from the 10th week of pregnancy, for both singleton and twin pregnancies.

    Non-surgical prenatal screening can also be combined with other advanced scientific services including storing baby's stem cells from umbilical cord blood at birth.

    What is the principle of non-invasive prenatal testing?



    During pregnancy, some of the baby's DNA travels from the placenta into the bloodstream. A sample of the mother's blood is drawn, and this test checks for DNA in order to determine the number and status of certain chromosomes in the fetus.
    Using an advanced technique called 'mass parallel sequencing', millions of DNA fragments are analyzed for each sample, accurately counting the number of chromosomes present and determining whether there is an extra or a missing number of copies of these chromosomes in the child.

    What is a non-surgical prenatal examination?

    Non-invasive prenatal screening is a revolutionary advance in prenatal screening that can study a fetus's genetic material (DNA) by analyzing the mother's blood.
    In the past, the study of fetal DNA required more invasive methods such as amniocentesis or placental biopsies, which are not without risks for mothers and their babies.
    Non-invasive prenatal screening is a simple, high-accuracy test that helps avoid invasive, deeply invasive techniques to detect certain diseases before birth.
    These non-surgical prenatal tests enable you to screen for the most common chromosomal abnormalities that could affect your baby's health in the future using a simple blood test.

    You can do this non-invasive test from the 10th week of pregnancy, for both singleton and twin pregnancies.

    Key Features of Non-Surgical Prenatal Screening:

    • One tube of blood is drawn.
    • You can do it as early as 10 weeks of pregnancy (first trimester).
    • It gives a 99% accuracy in diagnosing trisomy 21, 18 and 13 - Down syndrome, Edwards syndrome and Patau syndrome.
    • It has the highest success rates.
    • Doctors will receive results within 5-7 days.

    For whom is a non-surgical prenatal test performed?

    Science has developed tremendously at the present time, and the non-invasive fetal DNA examination offers many benefits for diagnosis in the event that the fetus has some chromosomal disorders, as it is used to learn important and accurate information about the health of your developing child in the first three months (ie in the 10th week) of the fetus’s life, With little or no risk to pregnancy. This examination can be performed in Turkey Today.

    You may consider this examination as an option for you in one of the following situations:

    • If you were 35 or older at the time of birth (32 or older in the case of twins)
    • If your serum test result is abnormal or “positive”
    • If the ultrasound shows concerns or abnormalities in the growth and/or development of the fetus
    • May be used by people with a personal or family history of genetic disorders (such as Down syndrome)

    In addition, as directed by Australian and international medical societies, all pregnant women, regardless of risk factors, have the opportunity to discuss and make choices regarding non-surgical prenatal testing and other available prenatal screening and diagnostic tests.

    Non-invasive prenatal testing

    Non-invasive prenatal testing

    What diseases can non-surgical prenatal tests detect?

    Chromosomes usually come in pairs. Most people have 23 pairs of chromosomes, with one pair determining sex. Men usually have an XY pair of sex chromosomes, and women usually have an XX pair of sex chromosomes.
    Any increase or decrease in the number of chromosomes can lead to mental or physical disabilities, with varying levels of severity.

    Non-surgical prenatal tests look for the presence of fewer or more copies of chromosomes that are often associated with these disabilities.

    • Our NIPT non-invasive prenatal test accurately detects many diseases such as:
    1.  Having an extra copy of chromosome 21 (Down syndrome).
    2.  Having an extra copy of chromosome 18 (Edwards syndrome).
    3.  Having an extra copy of chromosome 13 (Patau syndrome).
    4.  Aneuploidy of the sex chromosome (change in number).

    As for the NIPT 46 test, it is expanded to include the examination of all 23 pairs of chromosomes, such as:

    1. Examination of chromosomes 1 through 22 (including 21, 18, and 13 tested by the previous screening), to look for changes in number and the loss or increase of small portions of the chromosomes.
    2. The search for a specific aneuploidy of the sex chromosome.

    Your doctor may have some clinical observations that prompt him to order another test, the NIPT Plus test, in which case he will look for the presence of very rare genetic syndromes caused by the loss of a very small portion of a chromosome. Here it should be noted that the NIPT Plus test cannot be performed on twins.
    Also, detection of changes in the number of sex chromosomes is only available for a single pregnancy (one fetus).

    How does a woman prepare for a non-surgical prenatal test in Turkey?

    A noninvasive prenatal test may be done when a woman has been at least 10 weeks pregnant, depending on what condition the doctor is looking at. Before the test, the woman undergoes an ultrasound to check the age and development of the fetus. You may also receive a counseling to help her prepare for the test results.

    How are women informed of the results of a non-invasive test in Turkey?

    Your test report will include one of two possible results for chromosomes 21, 18, 13 and the sex chromosomes. If your test was NIPT 46, you'll also get a result for all of your other chromosomes:

    1. Low-risk result - means the expected number of chromosomes were found
    2. A high-risk result - means that there are too many or too few copies of a chromosome. A diagnostic test is recommended to confirm the result and should be discussed by your doctor.

      fetus and chromosomes

      fetus and chromosomes

    What do NIPT test results mean?

    Non-invasive prenatal testing detects chromosomal conditions, but does not diagnose them. The test cannot tell you for sure whether your child has a chromosomal disorder.

    If testing indicates that your child is at risk of developing a chromosomal condition, your doctor may recommend further testing to confirm the diagnosis. These tests may be more invasive and include:

    • Amniocentesis: The fetus is surrounded by amniotic fluid, a water-like substance that contains fetal cells. Amniocentesis is a procedure in which a small amount of amniotic fluid (less than 1 ounce) is taken with a fine needle inserted into the uterus through the abdomen, under ultrasound guidance. The fluid is then sent to a laboratory for analysis. This test can be done between 14-20 weeks of pregnancy. This operation can not be performed if a premature birth is suspected.
    • Chorionic villus sampling: Chorionic villi are small parts of the placenta made up of a fertilized egg, so they usually have the same genes as a fetus. For a chorionic villus sampling test, a small sample of chorionic villus cells is taken from the placenta where they attach to the uterine wall. There are two ways to take the cells: either through the vagina and cervix, or through the abdomen. The chorionic villi sample is then sent to a laboratory where the cells are grown in a special fluid and tested after a few days. This test can be done between weeks 10 and 13 of the fetus's life.

    These examinations and tests help to determine the genetic disorder that the fetus may suffer from. They are also used to test the paternity and diagnose the fetus's infection with any infection and to ensure the maturity of the lung.

    Does a low-risk non-invasive prenatal test result mean that my baby will be healthy?

    The Non-Surgical Prenatal Test Kit is an advanced, non-invasive, high-resolution examination. However, no test guarantees that a child will not have any medical problems.

    Non-invasive prenatal testing deals with only specific chromosomal changes. It does not test or diagnose all genetic and non-genetic problems that may be present in a child.

    Bimaristan Medical Center remains your first choice for treatment in Turkey.
    We direct you to the best specialists who are experts in all fields, we break the language barrier, Arab specialist doctors will help you in communicating with your doctor, we help you book an appointment in the most important and modern hospitals in Turkey, we offer our services to secure hotel reservations for you and your companions, in addition to transportation, we help you secure a travel visa for you for free.
    We provide our services throughout Turkey, the best place to provide you with treatment is our destination.
    We accompany you step by step towards recovery.
    Free consultations around the clock.
    don't hesitate toContact usBimaristan, your family center in Turkey. You can also read on our website about Artificial Vaccination in Turkey.

    Frequently Asked Questions About Non-Surgical Prenatal Test in Turkey

    How does fetal DNA analysis work in Turkey?

    The non-invasive (non-surgical) examination that is conducted during pregnancy without interfering with the course of pregnancy or affecting its safety is considered the first option now.

    What is a NIPT test?

    Known as the prenatal cell-free DNA test, it is an analysis of a blood sample from the mother in which we can study the fetal DNA and address any disorders that may be present.

    What is the blood analysis to detect fetal abnormalities in Turkey?

    It is the same as non-surgical prenatal tests, a method that uses a sample of the mother's blood to detect the possibility of genetic diseases in the fetus.

    What is a DNA test to find out the gender of the fetus?

    A non-surgical prenatal test enables us to determine the sex of the fetus from the second month and there is no need to wait for the fourth month for the genitals to appear and be visible on the ultrasound.

    What is the accuracy rate of non-invasive prenatal examination?

    According to the most important current studies on this subject, the sensitivity of this test reached 100% for the detection of Down syndrome, 92.9% with the sensitivity of detecting trisomy 18, and 100% also the amount of sensitivity for the detection of trisomy 13.

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